Week 1
To-Do List
- Lecture Activities
- Complete Lecture Questions Week 1
- Complete You’re the Professor! Week 1
By the end of lecture 1.1 on Introduction to Microbes, students will be able to…
- Understand the concept of microorganisms and how tiny they are.
- Describe microbial pathogenesis and the techniques to fight them.
- Identify the differences between pathogens and non-pathogen microbes.
- Differentiate prokaryotes, eukaryotes, and viruses.
- Understand the importance of light and its properties for microscopy.
By the end of lecture 1.2 on Prokaryotes & Eukaryotes, students will be able to
- Understand how prokaryotes are differentiated from eukaryotes.
- Identify eukaryotic cells and the differences across eukaryotic species.
- Describe the major external features of bacteria.
- Recognize cell morphology, arrangement, and gram-positive vs gram-negative.
- Differentiate the various internal features of bacteria.
Week 2
To-Do List
- Assessments
- Lecture Activities
- Complete Lecture Questions Week 2
- Complete You’re the Professor! Week 2
By the end of lecture 2.1 on Microbial Genetics I, students will be able to…
- Describe nucleic acids and how they bind to each other.
- Recognize how DNA is transcribed to RNA.
- Identify the RNA sequence to produce proteins.
- Explain the formation and structure of proteins.
By the end of lecture 2.1 on Microbial Genetics II, students will be able to…
- Recognize how DNA is represented and drawn.
- Explain how DNA is replicated.
- Differentiate leading and lagging strands.
- Identify how DNA is passed on to daughter cells.
Week 3
To-Do List
- Lecture Activities
- Complete Lecture Questions Week 3
- Complete You’re the Professor! Week 3
By the end of lecture 3.1 on Bacterial Genes Regulation, students will be able to…
- Describe how bacterial genes are regulated.
- Recognize how lac operon is regulated with lactose and glucose.
- Interpret various lac operon scenarios to determine transcription level.
By the end of lecture 3.2 on Applications of Microbial Genetics, students will be able to…
- Understand the purpose of restriction enzyme in making recombinant DNA.
- Describe the steps of molecular cloning.
- Recognize the role of PCR in identifying successfully cloned colonies.
- Identify the impacts of plastic on the environment.
- Explain how enzymes from I. sakaiensis can breakdown plastics.
Week 4
To-Do List
By the end of lecture 4.1 on CRISPR Technology & Ethics in Microbiology, students will be able to…
- Identify each step of the phage life cycle.
- Understand how bacteria use CRISPR-Cas9 to defend against phage.
- Recognize the role of CRISPR-Cas9 in the context of gene editing.
Week 5
To-Do List
- Lecture Activities
- Complete Lecture Questions Week 5
- Complete You’re the Professor! Week 5
By the end of lecture 5.1 on Microbial Metabolism I, students will be able to
- Identify the main unit of energy for organism metabolism.
- Understand activation and Gibbs free energy for exergonic and endogenic reactions.
- Describe the role and structure of enzyme.
- Explain how enzymes are controlled and affected by temperature and pH.
By the end of lecture 5.2 on Microbial Metabolism II, students will be able to
- Recognize how substrate and enzyme concentration affect the rate of reaction.
- Understand the importance of enzymes in breakdown sugar.
- Explain how sugar molecules are broken down to pyruvate through glycolysis.
- Identify the purpose of the Krebs cycle / TCA cycle.
- Recognize how electron transport chain can produce ATP.
Week 6
To-Do List
- Assessments
- Lecture Activities
- Complete Lecture Questions Week 6
- Complete You’re the Professor! Week 6
By the end of lecture 6.1 on Microbial Growth & Control, students will be able to…
- Describe bacterial growth in optimal environments.
- Understand how to count bacterial cells using spectrophotometry.
- Explain how bacterial cells form biofilms and their effect on healthcare.
- Describe the physical and chemical methods used for microbial control.
By the end of lecture 6.2 on Antimicrobial Drugs: Antibiotics, students will be able to…
- Identify the appropriate laboratory biological safety levels for lab work.
- Define the terms cleaning, sanitizing, disinfection, and sterilization.
- Describe the physical methods used for microbial control.
- Explain the mechanisms by which chemical agents control microbial growth.
Week 7
To-Do List
- Lecture Activities
- Complete Lecture Questions Week 7
- Complete You’re the Professor! Week 7
By the end of lecture 7.1 on Antibiotic Resistant Infection, students will be able to…
- Explain the significance of “opportunistic pathogen”.
- Understand how S. aureus becomes antibiotic resistant.
- Define hospital-acquired infections.
- Recognize the causes of hospital-acquired infections.
By the end of lecture 7.2 on Viruses & Vaccines, students will be able to…
- Describe the features and life cycle of viruses.
- Recognize how influenza evolves and can be detected.
- Understand how SARS-CoV-2 (COVID-19) is transmitted.
- Identify the various treatments possible against COVID-19.
- Explain the mechanisms behind mRNA and traditional vaccines.
Week 8
To-Do List
- Assessments
- Take Exam #2, Starting at 11:30 AM
By the end of lecture 8.1 on Viral Infections & Bacteriophages, students will be able to…
- List the different types and lengths of infections.
- Identify the impact of HIV infection and viral latency.
- Describe the lytic and lysogenic cycle of bacteriophages.
- Understand how bacteriophages attach and penetrate the host cells.
- Explain how viral proteins are made and how virions are released.
- Recognize the benefits of bacteriophage therapy.
Week 9
To Do List
- Lecture Activities
- Complete Lecture Questions Week 9
- Complete You’re the Professor! Week 9
By the end of lecture 9.1 on Person-to-Person Microbial Diseases, students will be able to…
- Understand how respiratory diseases can spread among people.
- Describe how SARS-CoV-2 evolve and its implications on human infection.
- Recognize the importance of vaccines to fight against measles virus.
By the end of lecture 9.2 on Nonspecific Host Defenses, students will be able to
- Explain how the microbiome protects the body from pathogens.
- Identify the main physical barriers that prevent pathogen entry into the body.
- Describe how chemical secretions help destroy or inhibit pathogens.
- Recognize how the inflammatory response helps recruit immune cells.
Week 10
To Do List
- Assessments
- Lecture Activities
- Complete Lecture Questions Week 10
- Complete You’re the Professor! Week 10
By the end of lecture 10.1 on Nonspecific Host Defenses, students will be able to
- Explain the various cellular defenses against microbes.
- Understand how the cellular defenses act against a pathogen.
- Recognize that an overreaction of cellular defenses can lead to cytokine storms.
By the end of lecture 10.2 on Adaptive Host Defenses, students will be able to
- Compare the characteristics of innate and adaptive immunity.
- Explain how dendritic cells initiate the adaptive immune response.
- Describe the role of CD4+ helper T cells and CD8+ cytotoxic T cells.
Week 11
To Do List
- Lecture Activities
- Complete Lecture Questions Week 11
- Complete You’re the Professor! Week 11
By the end of lecture 11.1 on Adaptive Host Defenses II, students will be able to…
- Explain the functions of helper T (Th) cells in activating B cells.
- Describe CD8+ T cell-mediated cytotoxicity.
- Recognize the structure and roles of antibody.
- Identify how B cell activates and differentiate.
- Understand the lymphatic system and how it keeps the host from infections.
By the end of lecture 11.2 on Human Microbiomes & Allergies, students will be able to…
- Understand how sequencing is used to identify genome of microbiomes.
- Recognize the importance of studying microbiomes.
- Recognize how the hygiene hypothesis may result in allergies.
- Understand type I hypersensitivity and the effect of histamine.
- Describe type II hypersensitivity and blood transfusion to another person.
Week 13
To Do List
- Lecture Activities
- Complete Lecture Questions Week 13
- Complete You’re the Professor! Week 13
By the end of lecture 13.1 on Parasitic Infectious Diseases, students will be able to…
- Identify and describe the three most common categories of parasitic infections.
- Explain life cycles and transmission of major soil parasites.
- Analyze health impact of malaria and connect it to sickle cell anemia.
- Evaluate the risks of food-borne parasitic infections and how to avoid them.
By the end of lecture 13.2 on Foodborne Microbial Diseases, students will be able to…
- Understand why the fridge or freezer is essential for food storage.
- Identify the methods to store food safely from pathogens.
- Recognize the different infectious strains of E. coli.
- Describe the symptoms of S. aureus and Salmonella infection.
- Explain how H. pylori and C. difficile affect the digestive tract.
Week 14
To Do List
- Assessments
- Lecture Activities
- Complete Lecture Questions Week 14
- Complete You’re the Professor! Week 14
By the end of lecture 15.1 on Waterborne Microbial Diseases, students will be able to…
- Understand where Vibrio cholerae comes from and its life cycle.
- Recognize the importance of John Snow’s work in solving cholera outbreak.
- Explain the concept of antibiotic resistance and how it impacts global health.
- Discuss the factors contributing to antibiotic resistance among refugees.
- Understand antibiotic resistance in altered gut microbiota for public health.
- Describe strategies to address antibiotic resistance among refugees.
Final Week: Take Final Exam